Inactiva Labs
PUBLISHED POSITIVE RESULTSNEGATIVE DATA

We generate the other 94%.

94% of drug failure data is never published.

Inactiva Labs runs automated robotic assays to produce the negative pharmaceutical data that AI models need — but no one collects.

THE PROBLEM

The missing half of pharmaceutical data.

Publication bias silently distorts drug development. Negative results vanish, billions are wasted, and only a fraction of candidates survive — all because half the evidence never makes it to the table.

~0%
of negative results get publishedSource: Turner et al., NEJM 2008
$1.4B
average cost of a failed drug trialSource: Bian et al., ScienceDirect 2025
1 in 10
drugs that enter trials ever get approvedSource: Congressional Budget Office

Publication bias breakdown

Positive results published94%
Negative results published6%

Built on peer-reviewed research from NEJM, ScienceDirect, and the Congressional Budget Office

The Data Gap

A 58% performance gap.
Billions left on the table.

MCC (Matthews Correlation Coefficient) measures how well AI models predict drug outcomes. With balanced data, accuracy jumps dramatically.

Based on published benchmarks comparing biased vs. balanced training datasets.

Current AI Drug Prediction0.48–0.55

Current AI drug prediction accuracy

vs
With Inactiva's Balanced Data0.75+

Predicted accuracy with balanced negative data

The Solution

The world's first negative
pharmaceutical data foundry.

High-throughput robotic foundry generating standardized, validated negative data across four axes:

01

Solubility

Compounds that fail dissolution — the most common early-stage failure mode. — Know which compounds dissolve before wasting months in the lab.

02

Permeability

Compounds that cannot cross biological membranes — critical for oral bioavailability. — Predict oral drug viability early.

03

Stability

Compounds that degrade under physiological conditions before reaching their target. — Eliminate unstable candidates before costly trials.

04

Toxicity

The most expensive failure mode. Structured negative toxicity data no public dataset contains. — Catch toxic compounds before they reach patients.

Ready to move forward?

Ready to see how it works? Partner with us.

See How It Works
THE SCIENCE

From robot to dataset
in hours, not months.

End-to-end automated pipeline — robot to ML-ready dataset.

01

Custom Robot

Custom-built 3D-printed liquid handler (<$600 to build) designed for high-throughput screening.

02

PEG Stress Test

Automated stress test pushes proteins across hundreds of conditions per run to find their breaking points.

03

Optical Measurement

Real-time light-based measurement detects if a protein clumps — a key failure signal.

04

Data Logged

Every result — pass or fail — is logged into clean, standardized datasets ready for machine learning.

Structural Moat

A cost advantage
competitors can't match.

Commercial Arms$150k+
  • Locked proprietary software
  • Expensive service contracts
  • Months to reconfigure an assay
vs
Inactiva Custom Robots$3k – $15k
  • Unified Python orchestration
  • Push code to change protocol
  • Full fleet for price of one arm
65%

Lower operating costs vs United States

10x

Robot fleet for the price of one arm

0

Direct competitors in negative pharma data

Get in Touch

Let's talk.

Whether you're an investor, pharma partner, or researcher — we'd love to hear from you.

Inactiva Labs

The data that drugs
are missing.

The world's first negative pharmaceutical data foundry. Join us before the window closes.

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